Chiral Auxiliaries in Polymer-Supported Organic Synthesis
نویسندگان
چکیده
منابع مشابه
Chiral Auxiliaries in Asymmetric Synthesis
Background The use of chiral auxiliaries in the synthesis of enantiomerically pure compounds has found wide application for a variety of reactions over the last three decades. Despite the extensive developments in this area by many academic and industrial research groups, new auxiliary controlled reactions continue to evolve frequently [1]. First objectives in this area have been to develop chi...
متن کاملSoluble polymer-supported organic synthesis.
Soluble polymers have been used as supports for reagent/catalyst immobilization and synthesis. Two polymers are commonly used in this context, linear polystyrene and poly(ethylene glycol). The complementary solubility properties of these polymers allow access to a wide range of chemistries. Parallel and combinatorial libraries of small molecules have been prepared using these polymers, and reag...
متن کاملSulfur- and selenium-based linkers in polymer-supported organic synthesis
The use of sulfurand selenium-based linkers in polymer-supported organic synthesis (PSOS) is reviewed. The literature describing the application of sulfur-based linkers in the PSOS of small molecules and combinatorial library preparation from 2000 to the present is summarized. The development and use of selenium-based linkers in PSOS, highlighting the work of the Nicolaou and Huang groups, is a...
متن کاملRecent applications of polymer supported organometallic catalysts in organic synthesis.
Recent developments concerning the application of polymer supported organometallic reagents in solid phase synthesis are reviewed, with a special focus on methodology for carbon-carbon formation. Examples of reactions that are covered include the classical Suzuki, Sonogashira and Heck coupings, but also aryl amination, epoxide opening, rearrangements, metathesis and cyclopropanation. Applicatio...
متن کاملSynthesis of Functionalized Aryl-vinyl Ethers as Building Blocks and Auxiliaries in Organic Synthesis
5- hydroxyisoquinoline undergoes a smooth reaction with alkyl propiolates in the presence of triphenylphosphine (15 mol%) to produce the corresponding (E)-alkyl 3-(isoquinolin-5-yloxy) acrylate in good yields. When the reaction was performed by 2-methyl 4-hydroxyquinoline and 3-nitro 4-hydroxypyridine, similar aryl vinyl ethers were obtained.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: ChemInform
سال: 2004
ISSN: 0931-7597,1522-2667
DOI: 10.1002/chin.200424217